Centers, National Poison Data System (NPDS)
2/17/09
Chemical exposures
Compiled by Lesly Federici
1. Exposures in pregnancy
Exposure during pregnancy occurred in 9,015 (0.36% of all human exposures) of women. Of those with known pregnancy duration (N = 8,325):
32.9% occurred in the first trimester,
37.0% in the second trimester, and
30.1% in the third trimester.
Most (73.8%) were unintentional and 19.5% were intentional exposures.
2. Route of Exposures (top 3):
Ingestion 78.4% (2,045,110)
Dermal 7.3% (191,298)
Inhalation/nasal 5.6% (145,552)
3. Site of Call and Exposures:
Site of Call (home residence) 74.43%
Site of exposure (home residence) 90.00%
4. Age/Gender of distribution of Human Exposures
<1 yr: ( 51%) Male – 67,874 / (47%)F – 62,456
1 year: (52%) M – 206,907 / (47.81%) F – 190,049
2 years: (52.55%) M – 219,534 / (47.28%)F – 197,520
3 years: (55.18%) M - 101884 / (44.61%) F – 82,371
4 years: (56.27%) M – 48,842 / (43.45) F – 37,713
5 years: (57.14%) M – 28,521 /F (42.43%) 21,180
5. Distribution of Reason for Exposure by Age
Unintentional:
<6years: 61.2% (1,263,194)
6 – 12: 6.8% (139,848)
13 – 19: 3.9% (80,175)
>19: 27.4% (565,560
6. Distribution of Reason for Exposures and Age for Fatalities
Unintentional:
General: <6:13, 6-12:2, 13-19:1, >19:18
Environmental: <6:10, 6-12:6, 13-19:0, >19:39
7. Substances Most Frequently Involved in Human Exposures (top three out of 25)
1. Analgesics 12.5% (309,431)
2. Cosmetics/personal care products 9.1% (225,410)
3. Cleaning substances/household 8.7% (216.228)
8. Substances Most Frequently Involved in Pediatrics
(<5 years) exposures (top three out of 25)
1.Cosmetics/personal care products 10.7% (172,541)
2.Cleaning substances/household 7.6% (122,832)
3.Analgesics 7.2% (115,059)
9. Trends
1985 – 886,389 – total human exposures
<6 years: 64.2%
2007 -2,482,041 – total human exposures
<6 years: 51.2%